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<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" lang="en"><head><title></title><meta http-equiv="Content-Type" content="text/html; charset=utf-8"><meta name="viewport" content="width=device-width, initial-scale=1.0"><!--[if mso]><xml><o:OfficeDocumentSettings><o:PixelsPerInch>96</o:PixelsPerInch><o:AllowPNG/></o:OfficeDocumentSettings></xml><![endif]--><style>*{box-sizing:border-box}body{margin:0;padding:0}a[x-apple-data-detectors]{color:inherit !important;text-decoration:inherit !important}#MessageViewBody a{color:inherit;text-decoration:none}p{line-height:inherit}.desktop_hide,.desktop_hide table{mso-hide:all;display:none;max-height:0;overflow:hidden}@media(max-width:620px){.image_block img.big,.row-content{width:100% !important}.mobile_hide{display:none}.stack .column{width:100%;display:block}.mobile_hide{min-height:0;max-height:0;max-width:0;overflow:hidden;font-size:0}.desktop_hide,.desktop_hide table{display:table !important;max-height:none !important}}</style></head><body style="background-color: #FFFFFF; margin: 0; padding: 0; -webkit-text-size-adjust: none; text-size-adjust: none;"><span id="bsft-preheader" class="preheader" style="color: transparent; display: none; visibility: hidden; height: 0; max-height: 0; width: 0;max-width: 0; opacity: 0; overflow: hidden; mso-hide: all;">Sequencing.com is showing its support for Rare Disease Month: Be a part of the solution and help raise awareness.</span><table class="nl-container" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #FFFFFF;"><tbody><tr><td><table class="row row-1" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-1" width="100%" border="0" cellpadding="20" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad"><div class="alignment" align="center" style="line-height:10px"><a href="https://links.dna.sequencing.com/z/j8nivtiu8?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=dc66a3fa-d821-46cd-a7e7-ecf6084dc264&bsft_ek=2023-02-03T19%3A00%3A39Z&bsft_mime_type=html&bsft_tv=22&bsft_lx=1" target="_blank" style="outline:none" tabindex="-1"><img src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/Sequencing.com%20Logo_Dark_Center_Tag.png" style="display: block; height: auto; border: 0; width: 210px; max-width: 100%;" width="210"></a></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-2" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-1" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad" style="width:100%;padding-right:0px;padding-left:0px;"><div class="alignment" align="center" style="line-height:10px"><img class="big" src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/Leo_Mary_Table1.png" style="display: block; height: auto; border: 0; width: 600px; max-width: 100%;" width="600"></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-3" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-1" width="100%" border="0" cellpadding="10" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 14px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; mso-line-height-alt: 16.8px; color: #555555; line-height: 1.2;"><p style="margin: 0; mso-line-height-alt: 16.8px;"><span style="font-size:24px;"><strong><span style="color:#000000;">February is Rare Disease Month.</span></strong></span></p><p style="margin: 0; mso-line-height-alt: 16.8px;"> </p><p style="margin: 0; mso-line-height-alt: 28.799999999999997px;">For a large part of our Sequencing.com community, rare diseases are of utmost concern. Many of you have sought out our products and asked for our assistance in uncovering the genomic origins of your own health issues.</p><p style="margin: 0; mso-line-height-alt: 16.8px;"> </p><p style="margin: 0; mso-line-height-alt: 28.799999999999997px;">But you may wonder what good it does to know that you carry a genetic risk factor for an illness. What can you do if you discover that you have a rare disease?</p></div></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-4" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="41.666666666666664%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: middle; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-2" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad" style="padding-bottom:15px;padding-left:10px;padding-right:10px;padding-top:15px;"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 14px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; mso-line-height-alt: 16.8px; color: #555555; line-height: 1.2;"><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;">Recently, you may have heard about actor Chris Hemsworth, who discovered he carries a gene variant that is a risk factor for Alzheimer’s disease. You can read about it <a href="https://links.dna.sequencing.com/web-only/z/k0184v7ia?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=dc66a3fa-d821-46cd-a7e7-ecf6084dc264&bsft_ek=2023-02-03T19%3A00%3A39Z&bsft_mime_type=html&bsft_tv=22&bsft_lx=2" target="_blank" style="text-decoration: underline; color: #0068A5;" rel="noopener">here</a>. As this article makes clear, Hemsworth’s genes are not his destiny. He can do plenty to lower his chances of actually developing Alzheimer’s disease, from eating a healthy diet to getting plenty of exercise and social interaction.</p></div></div></td></tr></table></td><td class="column column-2" width="58.333333333333336%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: middle; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-2" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad" style="width:100%;padding-right:0px;padding-left:0px;padding-top:5px;padding-bottom:5px;"><div class="alignment" align="center" style="line-height:10px"><a href="https://links.dna.sequencing.com/z/k0184v7ia?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=dc66a3fa-d821-46cd-a7e7-ecf6084dc264&bsft_ek=2023-02-03T19%3A00%3A39Z&bsft_mime_type=html&bsft_tv=22&bsft_lx=3" target="_blank" style="outline:none" tabindex="-1"><img src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/Chris%20H_600w_2.png" style="display: block; height: auto; border: 0; width: 228px; max-width: 100%;" width="228"></a></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-5" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-1" width="100%" border="0" cellpadding="10" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 14px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; mso-line-height-alt: 16.8px; color: #555555; line-height: 1.2;"><p style="margin: 0; mso-line-height-alt: 16.8px;">That is an important message to remember: Once you know your genetic inheritance, you can also take proactive steps to prevent or mitigate its impact on your life.</p><p style="margin: 0; mso-line-height-alt: 16.8px;"> </p><p style="margin: 0; mso-line-height-alt: 16.8px;">This month, in honor of Rare Disease Month, we’re offering our <a href="https://links.dna.sequencing.com/web-only/z/xl9grl29x?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=dc66a3fa-d821-46cd-a7e7-ecf6084dc264&bsft_ek=2023-02-03T19%3A00%3A39Z&bsft_mime_type=html&bsft_tv=22&bsft_lx=4" target="_blank" style="text-decoration: underline; color: #0068A5;" rel="noopener">Whole Genome Sequencing Rare Disease Bundle</a> for $240 off. The bundle includes whole genome sequencing of 100% of your DNA combined with our next-gen Rare Disease Report which screens for more than 10,000 rare diseases, conditions, and traits.</p><p style="margin: 0; mso-line-height-alt: 16.8px;"> </p><p style="margin: 0; mso-line-height-alt: 16.8px;">If you already have your Genome Sequenced and are interested in learning if you have a Rare Disease please go to the <a href="https://links.dna.sequencing.com/web-only/z/sbz0569rj?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=dc66a3fa-d821-46cd-a7e7-ecf6084dc264&bsft_ek=2023-02-03T19%3A00%3A39Z&bsft_mime_type=html&bsft_tv=22&bsft_lx=5" target="_blank" style="text-decoration: underline; color: #0068A5;" rel="noopener">Report Marketplace</a> to see our <a href="https://links.dna.sequencing.com/web-only/z/tmkjez2fm?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=dc66a3fa-d821-46cd-a7e7-ecf6084dc264&bsft_ek=2023-02-03T19%3A00%3A39Z&bsft_mime_type=html&bsft_tv=22&bsft_lx=6" target="_blank" style="text-decoration: underline; color: #0068A5;" rel="noopener">Rare Disease screen</a>.</p></div></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-6" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="button_block block-1" width="100%" border="0" cellpadding="20" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad"><div class="alignment" align="center"><!--[if mso]><v:roundrect xmlns:v="urn:schemas-microsoft-com:vml" xmlns:w="urn:schemas-microsoft-com:office:word" href="https://dna.sequencing.com/rare-disease-month-2023/" style="height:38px;width:214px;v-text-anchor:middle;" arcsize="132%" stroke="false" fillcolor="#12306c"><w:anchorlock/><v:textbox inset="0px,0px,0px,0px"><center style="color:#ffffff; font-family:Arial, sans-serif; font-size:14px"><![endif]--><a href="https://links.dna.sequencing.com/z/xl9grl29x?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=dc66a3fa-d821-46cd-a7e7-ecf6084dc264&bsft_ek=2023-02-03T19%3A00%3A39Z&bsft_mime_type=html&bsft_tv=22&bsft_lx=7" target="_blank" style="text-decoration:none;display:inline-block;color:#ffffff;background-color:#12306c;border-radius:50px;width:auto;border-top:0px solid transparent;font-weight:400;border-right:0px solid transparent;border-bottom:0px solid transparent;border-left:0px solid transparent;padding-top:5px;padding-bottom:5px;font-family:'Helvetica Neue', Helvetica, Arial, sans-serif;font-size:14px;text-align:center;mso-border-alt:none;word-break:keep-all;"><span style="padding-left:20px;padding-right:20px;font-size:14px;display:inline-block;letter-spacing:normal;"><span dir="ltr" style="word-break: break-word; line-height: 28px;"><strong>View Rare Disease Bundle</strong></span></span></a><!--[if mso]></center></v:textbox></v:roundrect><![endif]--></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-7" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; 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