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<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" lang="en"><head><title></title><meta http-equiv="Content-Type" content="text/html; charset=utf-8"><meta name="viewport" content="width=device-width, initial-scale=1.0"><!--[if mso]><xml><o:OfficeDocumentSettings><o:PixelsPerInch>96</o:PixelsPerInch><o:AllowPNG/></o:OfficeDocumentSettings></xml><![endif]--><style>*{box-sizing:border-box}body{margin:0;padding:0}a[x-apple-data-detectors]{color:inherit !important;text-decoration:inherit !important}#MessageViewBody a{color:inherit;text-decoration:none}p{line-height:inherit}.desktop_hide,.desktop_hide table{mso-hide:all;display:none;max-height:0;overflow:hidden}@media(max-width:620px){.image_block img.big,.row-content{width:100% !important}.mobile_hide{display:none}.stack .column{width:100%;display:block}.mobile_hide{min-height:0;max-height:0;max-width:0;overflow:hidden;font-size:0}.desktop_hide,.desktop_hide table{display:table !important;max-height:none !important}.row-3 .column-1 .block-1.image_block td.pad,.row-4 .column-1,.row-5 .column-1,.row-5 .column-2 .block-2.image_block td.pad,.row-6 .column-1{padding:0 !important}}</style></head><body style="background-color: #07153d; margin: 0; padding: 0; -webkit-text-size-adjust: none; text-size-adjust: none;"><span id="bsft-preheader" class="preheader" style="color: transparent; display: none; visibility: hidden; height: 0; max-height: 0; width: 0;max-width: 0; opacity: 0; overflow: hidden; mso-hide: all;">Find out if you carry DNA markers for a rare disease.</span><table class="nl-container" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #07153d;"><tbody><tr><td><table class="row row-1 mobile_hide" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><div class="spacer_block" style="height:21px;line-height:21px;font-size:1px;"> </div></td></tr></tbody></table></td></tr></tbody></table><table class="row row-2" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #07153d;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #ffffff; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: middle; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-1" width="100%" border="0" cellpadding="20" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad"><div class="alignment" align="center" style="line-height:10px"><a href="https://links.dna.sequencing.com/z/v86hx34o3?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=164b50d4-cc6e-4a35-9324-bf9ae26ce5ad&bsft_ek=2023-02-10T18%3A00%3A39Z&bsft_mime_type=html&bsft_tv=12&bsft_lx=1" target="_blank" style="outline:none" tabindex="-1"><img src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/Sequencing.com%20Logo_Dark_Center_Tag.png" style="display: block; height: auto; border: 0; width: 210px; max-width: 100%;" width="210"></a></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-3" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #07153d;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #ffffff; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 0px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-1" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad" style="width:100%;padding-right:0px;padding-left:0px;"><div class="alignment" align="center" style="line-height:10px"><a href="https://links.dna.sequencing.com/z/cgt75q91z?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=164b50d4-cc6e-4a35-9324-bf9ae26ce5ad&bsft_ek=2023-02-10T18%3A00%3A39Z&bsft_mime_type=html&bsft_tv=12&bsft_lx=2" target="_blank" style="outline:none" tabindex="-1"><img class="big" src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/Layered_LaC_Laptop%20header2.png" style="display: block; height: auto; border: 0; width: 600px; max-width: 100%;" width="600"></a></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-4" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #07153d;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #ffffff; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 0px; padding-bottom: 0px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-1" width="100%" border="0" cellpadding="10" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 12px; mso-line-height-alt: 14.399999999999999px; color: #555555; line-height: 1.2; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;"><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="font-size:14px;">In recognition of Rare Disease Month, we are reaching out to encourage and support your exploration of how rare diseases might factor into your own genome.</span></p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 14.399999999999999px;"> </p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="font-size:14px;">Many people carry the variant for a rare disease in their DNA and don’t realize it because the disease may not manifest for years. DNA analysis can help. By looking at your genome, markers for rare diseases may be identified.</span></p></div></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-5" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #07153d;"><tbody><tr><td><table class="row-content" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #ffffff; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="58.333333333333336%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: middle; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-2" width="100%" border="0" cellpadding="10" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 12px; mso-line-height-alt: 14.399999999999999px; color: #555555; line-height: 1.2; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;"><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="font-size:14px;">This is why we developed our Rare Disease Screen, the world’s most comprehensive carrier screening and rare disease DNA report. Rare Disease Screen scans your DNA for more than 1,200 rare diseases, syndromes, conditions, and traits.</span></p></div></div></td></tr></table></td><td class="column column-2" width="41.666666666666664%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: middle; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-2" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad" style="padding-right:20px;width:100%;padding-left:0px;padding-top:5px;padding-bottom:5px;"><div class="alignment" align="center" style="line-height:10px"><a href="https://links.dna.sequencing.com/z/2rt229ivw?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=164b50d4-cc6e-4a35-9324-bf9ae26ce5ad&bsft_ek=2023-02-10T18%3A00%3A39Z&bsft_mime_type=html&bsft_tv=12&bsft_lx=3" target="_blank" style="outline:none" tabindex="-1"><img src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/Rare%20Disease%20Screen%20Icon.png" style="display: block; height: auto; border: 0; width: 113px; max-width: 100%;" width="113"></a></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-6" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #07153d;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #ffffff; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 0px; padding-bottom: 0px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-1" width="100%" border="0" cellpadding="10" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 12px; mso-line-height-alt: 14.399999999999999px; color: #555555; line-height: 1.2; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;"><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="font-size:14px;">You’ll find the<a href="https://links.dna.sequencing.com/web-only/z/2rt229ivw?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=164b50d4-cc6e-4a35-9324-bf9ae26ce5ad&bsft_ek=2023-02-10T18%3A00%3A39Z&bsft_mime_type=html&bsft_tv=12&bsft_lx=4" target="_blank" style="text-decoration: underline; color: #5eb0f3;" rel="noopener"> Rare Disease Screen</a> in our Report Marketplace. To run the Rare Disease Screen, use your existing data or purchase our<a href="https://links.dna.sequencing.com/z/4hxrml91a?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=164b50d4-cc6e-4a35-9324-bf9ae26ce5ad&bsft_ek=2023-02-10T18%3A00%3A39Z&bsft_mime_type=html&bsft_tv=12&bsft_lx=5" style="text-decoration: underline; color: #5eb0f3;"> Whole Genome Sequencing</a> kit, which sequences 100% of your genome.</span></p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 14.399999999999999px;"> </p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="font-size:14px;">Once you know your genetic inheritance, you can also take proactive steps to prevent or mitigate its impact on your life. Let Rare Disease Screen help you discover whether you carry the markers for a rare disease. </span></p></div></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-7" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #07153d;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #ffffff; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="button_block block-1" width="100%" border="0" cellpadding="30" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; 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