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<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" lang="en"><head><title></title><meta http-equiv="Content-Type" content="text/html; charset=utf-8"><meta name="viewport" content="width=device-width, initial-scale=1.0"><!--[if mso]><xml><o:OfficeDocumentSettings><o:PixelsPerInch>96</o:PixelsPerInch><o:AllowPNG/></o:OfficeDocumentSettings></xml><![endif]--><style>*{box-sizing:border-box}body{margin:0;padding:0}a[x-apple-data-detectors]{color:inherit !important;text-decoration:inherit !important}#MessageViewBody a{color:inherit;text-decoration:none}p{line-height:inherit}.desktop_hide,.desktop_hide table{mso-hide:all;display:none;max-height:0;overflow:hidden}@media(max-width:620px){.image_block img.big,.row-content{width:100% !important}.mobile_hide{display:none}.stack .column{width:100%;display:block}.mobile_hide{min-height:0;max-height:0;max-width:0;overflow:hidden;font-size:0}.desktop_hide,.desktop_hide table{display:table !important;max-height:none !important}.row-5 .column-2 .block-2.image_block td.pad{padding:0 !important}.row-7 .column-1 .block-1.button_block a span,.row-7 .column-1 .block-1.button_block div,.row-7 .column-1 .block-1.button_block div span{font-size:13px !important;line-height:2 !important}}</style></head><body style="background-color: #FFFFFF; margin: 0; padding: 0; -webkit-text-size-adjust: none; text-size-adjust: none;"><span id="bsft-preheader" class="preheader" style="color: transparent; display: none; visibility: hidden; height: 0; max-height: 0; width: 0;max-width: 0; opacity: 0; overflow: hidden; mso-hide: all;">See the impact of Sequencing.com's Rare Disease Screen on people's lives</span><table class="nl-container" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; background-color: #FFFFFF;"><tbody><tr><td><table class="row row-1" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 10px; padding-bottom: 10px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-1" width="100%" border="0" cellpadding="20" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad"><div class="alignment" align="center" style="line-height:10px"><a href="https://links.dna.sequencing.com/z/uneqm5xyl?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=df00c36d-3c5e-4371-adc9-3d0322efdf3b&bsft_ek=2023-02-23T16%3A00%3A38Z&bsft_mime_type=html&bsft_tv=28&bsft_lx=1" target="_blank" style="outline:none" tabindex="-1"><img src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/Sequencing.com%20Logo_Dark_Center_Tag.png" style="display: block; height: auto; border: 0; width: 210px; max-width: 100%;" width="210"></a></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-2" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 0px; padding-bottom: 0px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-1" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad" style="width:100%;padding-right:0px;padding-left:0px;"><div class="alignment" align="center" style="line-height:10px"><img class="big" src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/Rare%20Disease%20Screen%20Art3.png" style="display: block; height: auto; border: 0; width: 600px; max-width: 100%;" width="600"></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-3" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 10px; padding-bottom: 10px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-1" width="100%" border="0" cellpadding="10" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 12px; mso-line-height-alt: 14.399999999999999px; color: #555555; line-height: 1.2; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;"><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="color:#000000;"><strong><span style="font-size:22px;">Learn about our Rare Disease Community.</span></strong></span></p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 14.399999999999999px;"> </p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="font-size:14px;">The human genome has the potential to carry thousands of rare diseases. Because they are uncommon, healthcare professionals often have a harder time diagnosing them.</span></p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 14.399999999999999px;"> </p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="font-size:14px;">Many people in our Sequencing.com community, including Chris and Joanne below, have shared stories of their efforts to find a diagnosis for their rare health issues. They also describe the relief they felt once they solved the mystery with DNA sequencing.</span></p></div></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-4" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; background-color: #12306c; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 0px; padding-bottom: 0px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-1" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad" style="padding-bottom:10px;padding-top:20px;"><div style="font-family: sans-serif"><div class="" style="font-size: 14px; mso-line-height-alt: 16.8px; color: #555555; line-height: 1.2; font-family: Arial, Helvetica Neue, Helvetica, sans-serif;"><p style="margin: 0; font-size: 14px; text-align: center; mso-line-height-alt: 16.8px;"><span style="font-size:20px;color:#ffffff;"><strong>Testimonials</strong></span></p></div></div></td></tr></table><table class="text_block block-2" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad" style="padding-bottom:30px;padding-left:40px;padding-right:40px;padding-top:10px;"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 14px; font-family: Arial, 'Helvetica Neue', Helvetica, sans-serif; mso-line-height-alt: 16.8px; color: #555555; line-height: 1.2;"><p style="margin: 0; font-size: 14px; text-align: left; mso-line-height-alt: 16.8px;"><span style="color:#ffffff;">“My rare disease didn't present in full until I was 58. You also may be a carrier and not have symptoms, but your children or children's children might inherit. They can't treat it optimally if they have no idea what causes it! If you can be prepared for what could happen, your chances of getting help increase exponentially.”</span></p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"> </p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><em><span style="color:#ffffff;">- Chris T. Facebook</span></em></p><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"> </p><p style="margin: 0; mso-line-height-alt: 16.8px;"><span style="color:#ffffff;">“Thanks to the rare disease screen, I finally found out the reason for my lifelong hypothyroidism; a rare double-recessive mutation on the eighth chromosome, which causes a premature termination of the thyroglobulin protein during transcription.” </span></p><p style="margin: 0; mso-line-height-alt: 16.8px;"> </p><p style="margin: 0; mso-line-height-alt: 16.8px;"><em><span style="color:#ffffff;">– Joanne S. Facebook</span></em></p></div></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-5" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="50%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: middle; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-2" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad" style="padding-bottom:10px;padding-left:10px;padding-right:10px;padding-top:20px;"><div style="font-family: sans-serif"><div class="" style="font-size: 14px; mso-line-height-alt: 16.8px; color: #555555; line-height: 1.2; font-family: Arial, Helvetica Neue, Helvetica, sans-serif;"><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;">This month, in honor of Rare Disease Month, we’re offering our <a href="https://links.dna.sequencing.com/z/f2ryuwawy?uid=b5dd70e0-a350-4d06-ac9b-9ae02ff7deb8&mid=df00c36d-3c5e-4371-adc9-3d0322efdf3b&bsft_ek=2023-02-23T16%3A00%3A38Z&bsft_mime_type=html&bsft_tv=28&bsft_lx=2" style="text-decoration: underline; color: #0068A5;">Whole Genome Sequencing Rare Disease Day Bundle</a> for over $400 off. The bundle features whole genome sequencing of 100% of your DNA combined with our Next-gen Rare Disease Screen which screens for more than 10,000 rare diseases, conditions, and traits. In addition, the bundle also includes five more reports that will help you dive deeper into your health and well-being.</p></div></div></td></tr></table></td><td class="column column-2" width="50%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: middle; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="image_block block-2" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tr><td class="pad" style="padding-right:10px;width:100%;padding-left:0px;padding-top:5px;padding-bottom:5px;"><div class="alignment" align="center" style="line-height:10px"><img src="https://cdn.getblueshift.com/bee/images/a05d964a-6aef-4924-afa0-4efa74c00a50/WGS_Kit_Transp1.png" style="display: block; height: auto; border: 0; width: 270px; max-width: 100%;" width="270"></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-6" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table class="text_block block-1" width="100%" border="0" cellpadding="10" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; word-break: break-word;"><tr><td class="pad"><div style="font-family: Arial, sans-serif"><div class="" style="font-size: 12px; mso-line-height-alt: 14.399999999999999px; color: #555555; line-height: 1.2; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;"><p style="margin: 0; font-size: 14px; mso-line-height-alt: 16.8px;"><span style="font-size:14px;">As Chris says: Once you know your genetic inheritance, you can also take proactive steps to prevent or mitigate its impact on your life.</span></p></div></div></td></tr></table></td></tr></tbody></table></td></tr></tbody></table><table class="row row-7" align="center" width="100%" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt;"><tbody><tr><td><table class="row-content stack" align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; border-radius: 0; color: #000000; width: 600px;" width="600"><tbody><tr><td class="column column-1" width="100%" style="mso-table-lspace: 0pt; mso-table-rspace: 0pt; font-weight: 400; text-align: left; vertical-align: top; padding-top: 5px; padding-bottom: 5px; border-top: 0px; border-right: 0px; border-bottom: 0px; border-left: 0px;"><table c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